Supported by some human studies and substantial preclinical research
Lion's Mane Mushroom
Lion's Mane (Hericium erinaceus) is a medicinal mushroom with neuroprotective properties that may enhance cognitive function and support nerve growth factor (NGF) production. It has been used in traditional Chinese medicine for centuries and has gained popularity in modern nootropic stacks for its potential cognitive benefits.
Key Benefits
- May enhance cognitive function and memory
- Supports nerve growth factor (NGF) production
- Potential neuroprotective properties
- May reduce mild symptoms of anxiety and depression
- Supports overall brain health and neuroplasticity
Stacks Well With
Scientific Research
This 16-week study found that Lion's Mane supplementation improved cognitive function scores in adults with mild cognitive impairment compared to placebo.
This study demonstrated that Lion's Mane extract could stimulate neurite outgrowth and promote neural differentiation and regeneration.
This study found that Lion's Mane intake reduced depression and anxiety in female subjects over a 4-week period.
Community Reviews
Noticeable improvement in focus and memory
I've been taking Lion's Mane daily for about 3 months now, and I've noticed a significant improvement in my ability to focus for longer periods and recall information. I work in a demanding field that requires a lot of mental clarity, and this has been a game-changer for me. I take 1000mg twice daily with meals.
Subtle but effective for cognitive clarity
Unlike some supplements that you feel immediately, Lion's Mane has a more subtle effect that I noticed after about 2 weeks of consistent use. My thinking feels clearer, and I'm better able to articulate my thoughts. I also feel it helps with my occasional brain fog. The only reason for 4 stars instead of 5 is that it took some time to notice the effects.
Great for creative work
As a writer, I'm always looking for ways to enhance my creativity and mental stamina. Lion's Mane has been excellent for helping me maintain focus during long writing sessions. I've also noticed that I'm making more novel connections between ideas, which has improved my work. I take it with coffee in the morning and have experienced no side effects.
Works but causes some digestive issues
I can definitely tell this helps with my focus and mental clarity, but unfortunately it causes some digestive discomfort for me. I've found taking it with food helps somewhat. Still worth it for the cognitive benefits but be aware if you have a sensitive stomach.