W
Part of the Wellifi AI Health Ecosystem
Explore our AI-powered health and fitness solutions
Back to Nootropics
Lion's Mane Mushroom
Where to Buy
Host Defense
Capsules (120 count)
$29.99
Buy
Real Mushrooms
Powder (60g)
$27.95
Buy
Om Mushrooms
Powder (75g)
$24.99
Buy
Research Level
Moderate

Supported by some human studies and substantial preclinical research

Recommended by Dr. Andrew Huberman
Recommended by Dr. Paul Stamets

Lion's Mane Mushroom

4.7(183 reviews)

Lion's Mane (Hericium erinaceus) is a medicinal mushroom with neuroprotective properties that may enhance cognitive function and support nerve growth factor (NGF) production. It has been used in traditional Chinese medicine for centuries and has gained popularity in modern nootropic stacks for its potential cognitive benefits.

Key Benefits

  • May enhance cognitive function and memory
  • Supports nerve growth factor (NGF) production
  • Potential neuroprotective properties
  • May reduce mild symptoms of anxiety and depression
  • Supports overall brain health and neuroplasticity

Stacks Well With

Alpha GPC

Combines well for enhanced acetylcholine production and cognitive benefits

Bacopa Monnieri

Complementary memory-enhancing effects through different mechanisms

Vitamin B12

Supports nerve health and neurological function

Scientific Research

Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial
Mori K, Inatomi S, Ouchi K, Azumi Y, Tuchida T
Phytotherapy Research
2009

This 16-week study found that Lion's Mane supplementation improved cognitive function scores in adults with mild cognitive impairment compared to placebo.

Neurotrophic properties of the Lion's Mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia
Lai PL, Naidu M, Sabaratnam V, et al.
International Journal of Medicinal Mushrooms
2013

This study demonstrated that Lion's Mane extract could stimulate neurite outgrowth and promote neural differentiation and regeneration.

Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake
Nagano M, Shimizu K, Kondo R, et al.
Biomedical Research
2010

This study found that Lion's Mane intake reduced depression and anxiety in female subjects over a 4-week period.

Community Reviews

Sort by:
MT
Michael T.
Verified Purchase
March 15, 2023

Noticeable improvement in focus and memory

I've been taking Lion's Mane daily for about 3 months now, and I've noticed a significant improvement in my ability to focus for longer periods and recall information. I work in a demanding field that requires a lot of mental clarity, and this has been a game-changer for me. I take 1000mg twice daily with meals.

Product: Real Mushrooms Lion's Mane Extract
Dosage: 2000mg daily
JL
Jennifer L.
Verified Purchase
February 8, 2023

Subtle but effective for cognitive clarity

Unlike some supplements that you feel immediately, Lion's Mane has a more subtle effect that I noticed after about 2 weeks of consistent use. My thinking feels clearer, and I'm better able to articulate my thoughts. I also feel it helps with my occasional brain fog. The only reason for 4 stars instead of 5 is that it took some time to notice the effects.

Product: Host Defense Lion's Mane Capsules
Dosage: 1000mg daily
DW
David W.
January 22, 2023

Great for creative work

As a writer, I'm always looking for ways to enhance my creativity and mental stamina. Lion's Mane has been excellent for helping me maintain focus during long writing sessions. I've also noticed that I'm making more novel connections between ideas, which has improved my work. I take it with coffee in the morning and have experienced no side effects.

Product: Om Mushrooms Lion's Mane Powder
Dosage: 1500mg daily
SK
Sarah K.
Verified Purchase
December 12, 2022

Works but causes some digestive issues

I can definitely tell this helps with my focus and mental clarity, but unfortunately it causes some digestive discomfort for me. I've found taking it with food helps somewhat. Still worth it for the cognitive benefits but be aware if you have a sensitive stomach.

Product: Thrive Market Lion's Mane Capsules
Dosage: 1000mg daily
Write a Review
Share your experience with Lion's Mane Mushroom to help others make informed decisions.
Your Rating
Review Title
Your Review
Product Used
Dosage

Similar Nootropics

Bacopa Monnieri
Natural Nootropics
4.5
Bacopa Monnieri
An adaptogenic herb traditionally used in Ayurvedic medicine that may improve memory formation.
Alpha GPC
Cholinergics
4.6
Alpha GPC
A choline compound that may increase acetylcholine levels in the brain, supporting memory and learning.
Rhodiola Rosea
Natural Nootropics
4.5
Rhodiola Rosea
An adaptogenic herb that may help the body resist physical and mental stress while improving cognitive function.